Mononcytes and neutrophils are what type of cells (wandering/fixed)? wandering ê}|“â@Name the 2 modes of action Direct and Indirect Action ê}|“â@Name 5 examples of surface membrane barriers 1) Skin 2) Intact skin epidermis 3) Acid mantle of skin 4) Keratin 5) Intact Mucous Membranes 6) Mucus 7) Nasal Hairs 8) Cilia 9) Gastric Juices 10) Acid mantle of vagina 11) Lacrimal secretion 12) Urine 13) Oil (sebum) secretê}|“â@histocytes are located where and are which type of cell? located in skin, fixed macrophages ê}|“â@Where are microglia cells found and whicht ype of cell are they? In the nervous system, fixed macrophages ê}|“â@Mononcytes and neutrophils are located where? in the CVS ê}|“â@Name the first 4 steps in phagocytosis? 1) Chemotaxis 2) Adherence 3) Phagocyte forms pseudopods 4) Ingestion - engulfs particle and transports it in a vessicle (phagosome) ê}|“â@Name 2 types of cells in the nonspecific defenses phagocytes, NK cells ê}|“â@Name 4 Characteristics of Nonspecific Defenses 1) An inherited trait 2) Are mechanical barriers covering the body surfaces 3) Protect from pathogens 4) Respond immediately ê}|“â@What must happen to the immune system before a response can occur? Have an initial exposure to a foreign substance ê}|“â@The Immune System is a true organ system, true/false false ê}|“â@which type of action does this describe = releasing mobilizing chemicals and antibodies Indirect Action ê}|“â@Name 3 characteristics of phagocytes 1) engulf + destroy pathogens that breach surface barriers 2) macrophage also contribute to immune response 3) phagocytosis 4) Have both wandering and fixed macrophages 5) A type of non-specific defense ê}|“â@The Immune system is a functional system consisting of _________ cells ( _____, ______) immune cells (lymphocytes & Macrophages) ê}|“â@What is the first line of defense? Surface Membrane Barriers ê}|“â@Define Immunity resistance to disease ê}|“â@alveolar cells are which type of cell and where are they located? fixed macrophage, in lungs ê}|“â@Which type of defense = Will destroy any non-self cells indiscriminatly Nonspecific defense ê}|“â@Name the last 3 steps in phagocytosis 1) phagosome fuses w/ a lysosome forming a phagolysosome 2) Enzymes in phagolysosome digest the particle 3) residual matter is removed ê}|“â@which type of cell rips apart cells into basic units of bio. material lysosome ê}|“â@What type of cell (fixed/wandering) is a Kupffer cell and where is it located? fixed macrophages, in liver ê}|“â@